Issue 2 (December)

Mindfulness-Based Stress Reduction (MBSR) has emerged as a promising intervention for chronic pain management, emphasizing non-judgmental awareness of present moment experiences and cultivating adaptive coping strategies. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of MBSR in reducing pain intensity and improving overall functioning in individuals with chronic pain conditions. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of MBSR compared to control conditions (e.g., waitlist, treatment as usual, other interventions) in targeting chronic pain symptoms, including pain severity, pain interference, and psychological distress. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, frequency of sessions, therapist experience, and participant characteristics (e.g., pain duration, pain etiology), to better understand the factors influencing the effectiveness of MBSR for chronic pain management.

Interpersonal Psychotherapy (IPT) has been recognized as an effective intervention for Major Depressive Disorder (MDD), focusing on improving interpersonal relationships and addressing social role disputes, role transitions, grief, and interpersonal deficits. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of IPT in reducing depressive symptoms and improving overall functioning in individuals with MDD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of IPT compared to control conditions (e.g., waitlist, treatment as usual, other psychotherapies) in targeting symptoms of MDD, including depressed mood, anhedonia, psychomotor agitation or retardation, fatigue, and cognitive impairment. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of IPT for MDD.

Family-Based Therapy (FBT), also known as the Maudsley Approach, has been widely recognized as a leading intervention for adolescent Anorexia Nervosa (AN), emphasizing parental involvement and addressing family dynamics in the treatment process. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of FBT in reducing eating disorder symptoms and restoring healthy weight in adolescents with AN. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of FBT compared to control conditions (e.g., individual therapy, treatment as usual) in targeting symptoms of AN, including restrictive eating behaviors, excessive exercise, body image disturbances, and psychological distress. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, family involvement, and participant characteristics (e.g., age, duration of illness), to better understand the factors influencing the effectiveness of FBT for adolescent AN.

Cognitive Behavioral Therapy for Insomnia (CBT-I) has emerged as the first-line treatment for chronic insomnia, targeting maladaptive sleep-related behaviors and cognitions. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of CBT-I in improving sleep parameters and reducing insomnia severity in individuals with chronic insomnia. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of CBT-I compared to control conditions (e.g., waitlist, placebo, sleep hygiene education) in targeting insomnia symptoms, including sleep onset latency, wake after sleep onset, total sleep time, and sleep efficiency. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, delivery format (individual vs. group), therapist involvement, and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of CBT-I for chronic insomnia.

Mindfulness-Based Cognitive Therapy (MBCT) has emerged as a promising intervention for preventing relapse in individuals with recurrent depression, combining elements of cognitive therapy with mindfulness-based practices. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of MBCT in reducing depressive symptoms and preventing relapse in individuals with a history of recurrent depression. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of MBCT compared to control conditions (e.g., treatment as usual, maintenance antidepressants, placebo) in targeting depressive symptoms and preventing relapse/recurrence. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, frequency of sessions, therapist involvement, and participant characteristics (e.g., age, number of prior episodes), to better understand the factors influencing the effectiveness of MBCT for recurrent depression.

Dialectical Behavior Therapy (DBT) has been established as a leading intervention for Borderline Personality Disorder (BPD), emphasizing a dialectical approach that combines acceptance and change strategies to address emotional dysregulation and interpersonal difficulties. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of DBT in reducing BPD symptoms and improving overall functioning in individuals with BPD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of DBT compared to control conditions (e.g., treatment as usual, other psychotherapies) in targeting symptoms of BPD, including affective instability, impulsivity, self-harm behaviors, and interpersonal problems. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of DBT for BPD.

Acceptance and Commitment Therapy (ACT) has emerged as a promising intervention for chronic pain management, focusing on enhancing psychological flexibility and promoting values-based living in individuals with chronic pain conditions. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ACT in reducing pain severity and improving overall functioning in individuals with chronic pain. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ACT compared to control conditions (e.g., treatment as usual, waitlist, other psychotherapies) in targeting chronic pain symptoms, including pain intensity, pain interference, physical functioning, and emotional distress. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., pain duration, pain etiology), to better understand the factors influencing the effectiveness of ACT for chronic pain management.

Schema Therapy (ST) has gained recognition as a promising intervention for Borderline Personality Disorder (BPD), addressing maladaptive schemas and coping styles underlying persistent emotional dysregulation and dysfunctional interpersonal patterns. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ST in reducing BPD symptoms and improving overall functioning in individuals with BPD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ST compared to control conditions (e.g., treatment as usual, other psychotherapies) in targeting symptoms of BPD, including affective instability, identity disturbance, interpersonal problems, and impulsivity. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of ST for BPD.

Eye Movement Desensitization and Reprocessing (EMDR) therapy has emerged as a prominent intervention for Post-Traumatic Stress Disorder (PTSD), utilizing bilateral stimulation to facilitate the processing and integration of traumatic memories. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of EMDR therapy in reducing PTSD symptoms and improving overall functioning in individuals with PTSD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of EMDR therapy compared to control conditions (e.g., waitlist, other psychotherapies) in targeting symptoms of PTSD, including intrusive memories, avoidance behaviors, negative alterations in cognitions and mood, and hyperarousal. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, presence of comorbid conditions, and participant characteristics (e.g., trauma type, time since trauma), to better understand the factors influencing the effectiveness of EMDR therapy for PTSD.

Eye Movement Desensitization and Reprocessing (EMDR) therapy has emerged as a widely used intervention for Post-Traumatic Stress Disorder (PTSD), aiming to alleviate distressing symptoms by processing traumatic memories and fostering adaptive coping mechanisms. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of EMDR therapy in reducing PTSD symptoms and improving overall functioning in individuals with PTSD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of EMDR therapy compared to control conditions (e.g., waitlist, cognitive-behavioral therapy, supportive therapy) in targeting PTSD symptoms, including intrusive thoughts, avoidance behaviors, hyperarousal, and negative cognitions. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, trauma type (e.g., single-event trauma, complex trauma), and participant characteristics (e.g., age, gender), to better understand the factors influencing the effectiveness of EMDR therapy for PTSD.

Mindfulness-Based Stress Reduction (MBSR) has gained popularity as a therapeutic approach for anxiety disorders, aiming to cultivate mindfulness skills and promote acceptance of present-moment experiences. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of MBSR in reducing anxiety symptoms and improving overall well-being in individuals with anxiety disorders. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of MBSR compared to control conditions (e.g., waitlist, treatment as usual, other psychotherapies) in targeting anxiety symptoms, including generalized anxiety, social anxiety, panic attacks, and obsessive-compulsive symptoms. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, frequency of sessions, therapist involvement, and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of MBSR for anxiety disorders.

Interpersonal Psychotherapy (IPT) has been established as an effective intervention for Major Depressive Disorder (MDD), focusing on addressing interpersonal problems and enhancing social support to alleviate depressive symptoms. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of IPT in reducing depressive symptoms and improving overall functioning in individuals with MDD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of IPT compared to control conditions (e.g., treatment as usual, waitlist, other psychotherapies) in targeting depressive symptoms, including sadness, anhedonia, guilt, and psychomotor retardation. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, gender), to better understand the factors influencing the effectiveness of IPT for MDD.

Cognitive Behavioral Therapy (CBT) has emerged as a leading intervention for Generalized Anxiety Disorder (GAD), targeting maladaptive cognitive patterns and behavioral responses to reduce excessive worry and anxiety symptoms. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of CBT in reducing anxiety symptoms and improving overall functioning in individuals with GAD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of CBT compared to control conditions (e.g., waitlist, treatment as usual, relaxation therapy) in targeting GAD symptoms, including worry severity, somatic symptoms, and impairment in daily functioning. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of CBT for GAD.

Dialectical Behavior Therapy (DBT) has emerged as a gold standard intervention for Borderline Personality Disorder (BPD), targeting emotion dysregulation, impulsivity, and interpersonal difficulties to improve overall functioning and reduce self-harming behaviors. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of DBT in reducing BPD symptoms and improving quality of life in individuals with BPD. Through a comprehensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of DBT compared to control conditions (e.g., treatment as usual, waitlist, other psychotherapies) in targeting BPD symptoms, including emotional instability, interpersonal problems, self-harm, and suicidality. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, severity of symptoms), to better understand the factors influencing the effectiveness of DBT for BPD.

Acceptance and Commitment Therapy (ACT) has gained recognition as a promising intervention for chronic pain management, focusing on promoting psychological flexibility and enhancing patients' ability to pursue meaningful life activities despite pain. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ACT in reducing pain intensity and improving pain-related disability in individuals with chronic pain conditions. Through an exhaustive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ACT compared to control conditions (e.g., treatment as usual, waitlist, other psychotherapies) in targeting pain outcomes, including pain intensity, pain interference, and psychological distress. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and patient characteristics (e.g., pain duration, pain etiology), to better understand the factors influencing the effectiveness of ACT for chronic pain management.

Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) has emerged as a leading intervention for childhood trauma, aiming to address trauma-related symptoms and improve coping strategies in children and adolescents. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of TF-CBT in reducing trauma-related symptoms and improving overall functioning in youth with a history of trauma exposure. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of TF-CBT compared to control conditions (e.g., waitlist, treatment as usual, supportive therapy) in targeting trauma symptoms, including post-traumatic stress symptoms, depression, anxiety, and behavioral problems. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, type of trauma), to better understand the factors influencing the effectiveness of TF-CBT for childhood trauma.

Mindfulness-Based Cognitive Therapy (MBCT) has emerged as a promising intervention for preventing relapse and recurrence of depression, combining cognitive therapy techniques with mindfulness practices to target cognitive reactivity and promote self-regulation skills. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of MBCT in reducing depressive relapse/recurrence and improving overall well-being in individuals with a history of recurrent depression. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of MBCT compared to control conditions (e.g., treatment as usual, maintenance antidepressant medication, placebo) in preventing depressive relapse/recurrence and reducing residual depressive symptoms. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, frequency of sessions, therapist involvement, and participant characteristics (e.g., history of depression, comorbidities), to better understand the factors influencing the effectiveness of MBCT for recurrent depression.

Parent-Child Interaction Therapy (PCIT) has emerged as a leading intervention for disruptive behavior disorders in children, aiming to improve parent-child interactions and reduce problem behaviors through structured coaching and behavioral techniques. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of PCIT in reducing disruptive behavior symptoms and improving parent-child relationships in children with disruptive behavior disorders. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of PCIT compared to control conditions (e.g., waitlist, treatment as usual, parent education) in targeting disruptive behavior symptoms, including aggression, defiance, and conduct problems. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist involvement, treatment fidelity, and child characteristics (e.g., age, severity of symptoms), to better understand the factors influencing the effectiveness of PCIT for disruptive behavior disorders in children.

Exposure and Response Prevention (ERP) is considered the gold standard psychotherapy for Obsessive-Compulsive Disorder (OCD), focusing on exposing individuals to feared stimuli while preventing ritualistic responses to reduce symptom severity and improve functioning. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ERP in reducing OCD symptoms and improving quality of life in individuals with OCD. Through a comprehensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ERP compared to control conditions (e.g., waitlist, supportive therapy, medication only) in targeting OCD symptoms, including obsessions, compulsions, and associated impairment. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist involvement, treatment format (individual vs. group), and participant characteristics (e.g., age, symptom severity), to better understand the factors influencing the effectiveness of ERP for OCD.

Cognitive Processing Therapy (CPT) has emerged as a widely used and evidence-based treatment for Posttraumatic Stress Disorder (PTSD) in military veterans, focusing on cognitive restructuring techniques to address trauma-related beliefs and symptoms. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of CPT in reducing PTSD symptoms and improving overall functioning in military veterans with PTSD. Through an exhaustive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of CPT compared to control conditions (e.g., waitlist, treatment as usual, supportive therapy) in targeting PTSD symptoms, including re-experiencing, avoidance, hyperarousal, and negative cognitions. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., combat exposure, comorbidities), to better understand the factors influencing the effectiveness of CPT for PTSD in military veterans.

Dialectical Behavior Therapy (DBT) has become one of the leading treatments for Borderline Personality Disorder (BPD), focusing on enhancing emotion regulation skills, interpersonal effectiveness, distress tolerance, and mindfulness. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of DBT in reducing BPD symptoms and improving overall functioning in individuals with BPD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of DBT compared to control conditions (e.g., treatment as usual, supportive therapy, active control) in targeting BPD symptoms, including impulsivity, affective instability, identity disturbance, and interpersonal difficulties. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of DBT for BPD.

Acceptance and Commitment Therapy (ACT) has gained recognition as a promising intervention for Generalized Anxiety Disorder (GAD), emphasizing acceptance of distressing thoughts and feelings while promoting committed action toward values-based goals. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ACT in reducing GAD symptoms and improving overall functioning in individuals with GAD. Through a comprehensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ACT compared to control conditions (e.g., waitlist, treatment as usual, active control) in targeting GAD symptoms, including worry, somatic symptoms, and functional impairment. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of ACT for GAD.

Mindfulness-Based Stress Reduction (MBSR) has emerged as a popular intervention for chronic pain management, incorporating mindfulness meditation, yoga, and body awareness practices to cultivate nonjudgmental awareness and acceptance of pain sensations. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of MBSR in reducing pain intensity and improving pain-related outcomes in individuals with chronic pain conditions. Through an exhaustive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of MBSR compared to control conditions (e.g., waitlist, treatment as usual, active control) in targeting pain intensity, pain interference, physical functioning, and psychological well-being. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, adherence to practice, therapist involvement, and participant characteristics (e.g., pain duration, comorbidities), to better understand the factors influencing the effectiveness of MBSR for chronic pain management.

Motivational Interviewing (MI) has gained prominence as a patient-centered approach to addressing substance use disorders (SUDs), aiming to enhance intrinsic motivation for behavior change by exploring and resolving ambivalence. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of MI in reducing substance use and improving treatment outcomes in individuals with SUDs. Through a comprehensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of MI compared to control conditions (e.g., treatment as usual, psychoeducation, brief advice) in targeting substance use outcomes, including frequency, quantity, and severity of substance use, as well as treatment retention and engagement. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist adherence to MI principles, patient readiness to change, and substance type, to better understand the factors influencing the effectiveness of MI for SUDs.

Eye Movement Desensitization and Reprocessing (EMDR) has gained recognition as a psychotherapeutic approach for treating Posttraumatic Stress Disorder (PTSD), involving bilateral stimulation while processing traumatic memories to alleviate distress and promote adaptive resolution. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of EMDR in reducing PTSD symptoms and improving overall functioning in individuals with PTSD. Through a comprehensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of EMDR compared to control conditions (e.g., waitlist, cognitive-behavioral therapy, supportive therapy) in targeting PTSD symptoms, including re-experiencing, avoidance, hyperarousal, and negative cognitions. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., trauma type, comorbidities), to better understand the factors influencing the effectiveness of EMDR for PTSD.

Interpersonal Psychotherapy (IPT) has emerged as a structured and time-limited psychotherapeutic approach for treating Major Depressive Disorder (MDD), focusing on improving interpersonal functioning and resolving interpersonal problems that contribute to depressive symptoms. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of IPT in reducing depressive symptoms and improving overall functioning in individuals with MDD. Through an exhaustive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of IPT compared to control conditions (e.g., waitlist, cognitive-behavioral therapy, supportive therapy) in targeting depressive symptoms, including mood disturbance, interpersonal difficulties, and functional impairment. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of IPT for MDD.

Cognitive Behavioral Therapy (CBT) has been established as a first-line treatment for Generalized Anxiety Disorder (GAD), targeting maladaptive cognitive patterns and excessive worry through cognitive restructuring and exposure-based techniques. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of CBT in reducing GAD symptoms and improving overall functioning in individuals with GAD. Through a comprehensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of CBT compared to control conditions (e.g., waitlist, supportive therapy, relaxation training) in targeting GAD symptoms, including worry, physiological arousal, and functional impairment. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of CBT for GAD.

Dialectical Behavior Therapy (DBT) has emerged as a leading treatment for Borderline Personality Disorder (BPD), integrating cognitive-behavioral techniques with mindfulness and acceptance-based strategies to address emotion dysregulation, impulsivity, and interpersonal difficulties. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of DBT in reducing BPD symptoms and improving overall functioning in individuals with BPD. Through an exhaustive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of DBT compared to control conditions (e.g., treatment as usual, supportive therapy, waitlist) in targeting BPD symptoms, including affective instability, self-harm behaviors, and interpersonal problems. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist adherence to DBT principles, treatment setting (inpatient vs. outpatient), and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of DBT for BPD.

Acceptance and Commitment Therapy (ACT) has gained recognition as a transdiagnostic approach for treating anxiety disorders, emphasizing acceptance of internal experiences and commitment to value-based actions to foster psychological flexibility. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ACT in reducing anxiety symptoms and improving overall functioning in individuals with various anxiety disorders, including generalized anxiety disorder (GAD), social anxiety disorder (SAD), panic disorder (PD), and specific phobias. Through a comprehensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ACT compared to control conditions (e.g., waitlist, treatment as usual, active interventions) in targeting anxiety symptoms, including worry, fear, avoidance behaviors, and functional impairment. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist adherence to ACT principles, treatment format (individual vs. group), and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of ACT for anxiety disorders.

Mindfulness-Based Stress Reduction (MBSR) has emerged as a promising intervention for chronic pain management, emphasizing mindfulness meditation and body awareness to cultivate acceptance and reduce pain-related distress. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of MBSR in reducing pain intensity and improving pain-related outcomes in individuals with chronic pain conditions, such as fibromyalgia, low back pain, and arthritis. Through a thorough literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of MBSR compared to control conditions (e.g., waitlist, treatment as usual, active interventions) in targeting pain intensity, pain interference, physical functioning, and psychological distress. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, frequency of mindfulness practice, therapist experience, and participant characteristics (e.g., pain duration, comorbidities), to better understand the factors influencing the effectiveness of MBSR for chronic pain.