The Efficacy of Interpersonal Psychotherapy (IPT) for Major Depressive Disorder: A Meta-Analysis of Randomized Controlled Trials
Abstract
Interpersonal Psychotherapy (IPT) has been established as an effective intervention for Major Depressive Disorder (MDD), focusing on addressing interpersonal problems and enhancing social support to alleviate depressive symptoms. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of IPT in reducing depressive symptoms and improving overall functioning in individuals with MDD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of IPT compared to control conditions (e.g., treatment as usual, waitlist, other psychotherapies) in targeting depressive symptoms, including sadness, anhedonia, guilt, and psychomotor retardation. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, gender), to better understand the factors influencing the effectiveness of IPT for MDD.
Share and Cite
Article Metrics
References
- Klerman, G. L., et al. (1984). Interpersonal psychotherapy of depression. Basic Books.
- Cuijpers, P., et al. (2016). Interpersonal psychotherapy for depression: A meta-analysis. American Journal of Psychiatry, 173(7), 680-687.
- Markowitz, J. C., et al. (2015). Comparative efficacy of psychotherapies for depressed elders. Journal of Consulting and Clinical Psychology, 83(2), 304-312.
- Weissman, M. M., et al. (2000). Interpersonal psychotherapy for dysthymic disorder. Archives of General Psychiatry, 57(5), 464-469.
- Bockting, C. L., et al. (2015). Does publication bias inflate the apparent efficacy of psychological treatment for major depressive disorder? A systematic review and meta-analysis of US National Institutes of Health-funded trials. PLoS ONE, 10(9), e0137864.
- Stewart, R. E., et al. (2014). Interpersonal psychotherapy for depression: A meta-analysis. American Journal of Psychiatry, 171(11), 1209-1224.