Interpersonal Therapy (IPT) has shown promise as an intervention for Social Anxiety Disorder (SAD), addressing interpersonal difficulties and social skills deficits that contribute to anxiety in social situations. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of IPT in reducing social anxiety symptoms and improving overall functioning in individuals with SAD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of IPT compared to control conditions (e.g., waitlist, medication, other psychotherapies) in targeting symptoms of SAD, including fear of social evaluation, avoidance behavior, and impairment in social and occupational functioning. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, symptom severity), to better understand the factors influencing the effectiveness of IPT for SAD.

Mindfulness-Based Cognitive Therapy (MBCT) has emerged as a promising intervention for individuals with recurrent depression, combining elements of cognitive therapy with mindfulness practices to prevent relapse and reduce depressive symptoms. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of MBCT in reducing depressive relapse and improving overall well-being in individuals with recurrent depression. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of MBCT compared to control conditions (e.g., treatment as usual, maintenance antidepressants, other psychotherapies) in targeting depressive relapse rates, depressive symptoms severity, and quality of life. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, frequency of mindfulness practice, therapist guidance, and participant characteristics (e.g., history of depression, comorbidities), to better understand the factors influencing the effectiveness of MBCT for recurrent depression.

Acceptance and Commitment Therapy (ACT) has garnered attention as a promising intervention for Generalized Anxiety Disorder (GAD), focusing on acceptance of internal experiences and commitment to value-driven action. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ACT in reducing GAD symptoms and improving overall functioning in individuals with GAD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ACT compared to control conditions (e.g., waitlist, treatment as usual, other psychotherapies) in targeting symptoms of GAD, including excessive worry, somatic symptoms, and avoidance behaviors. Additionally, it examines potential moderators of treatment outcomes, such as treatment format (individual vs. group), treatment duration, therapist adherence, and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of ACT for GAD.

Exposure and Response Prevention (ERP) therapy has emerged as a leading intervention for Obsessive-Compulsive Disorder (OCD), targeting the core symptoms of obsessions and compulsions through systematic exposure to feared stimuli and prevention of ritualistic behaviors. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ERP in reducing OCD symptoms and improving overall functioning in individuals with OCD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ERP compared to control conditions (e.g., waitlist, medication, other psychotherapies) in targeting symptoms of OCD, including obsessions, compulsions, and associated distress. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, intensity, therapist experience, treatment format (individual vs. group), and participant characteristics (e.g., age, symptom severity), to better understand the factors influencing the effectiveness of ERP for OCD.

Dialectical Behavior Therapy (DBT) has shown promise as an intervention for eating disorders, addressing both the underlying emotional dysregulation and maladaptive behaviors associated with disordered eating. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of DBT in reducing eating disorder symptoms and improving overall well-being in individuals with eating disorders. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of DBT compared to control conditions (e.g., treatment as usual, other psychotherapies) in targeting symptoms of eating disorders, including restrictive eating, binge eating, purging behaviors, and body image disturbance. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist adherence, treatment setting, and participant characteristics (e.g., age, diagnosis subtype), to better understand the factors influencing the effectiveness of DBT for eating disorders.

Cognitive remediation therapy (CRT) has emerged as a promising intervention for schizophrenia, aiming to improve cognitive functioning and enhance daily functioning in individuals with the disorder. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of CRT in improving cognitive deficits and functional outcomes in individuals with schizophrenia. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of CRT compared to control conditions (e.g., treatment as usual, supportive therapy) in targeting cognitive domains such as attention, memory, executive function, and social cognition. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, intensity, adjunctive interventions, and participant characteristics (e.g., age, duration of illness), to better understand the factors influencing the effectiveness of CRT for schizophrenia.

Family therapy has been recognized as a valuable intervention for adolescent conduct disorder, targeting family dynamics and communication patterns that contribute to behavioral problems. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of family therapy in reducing conduct disorder symptoms and improving family functioning in adolescents. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of family therapy compared to control conditions (e.g., treatment as usual, individual therapy) in targeting conduct disorder symptoms, including aggression, rule-breaking behavior, and defiance. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, family involvement, and adolescent characteristics (e.g., age, gender), to better understand the factors influencing the effectiveness of family therapy for adolescent conduct disorder.

Psychodynamic therapy has long been considered a valuable intervention for personality disorders, addressing underlying conflicts and relational patterns that contribute to symptomatology. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of psychodynamic therapy in reducing symptom severity and improving overall functioning in individuals with personality disorders. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of psychodynamic therapy compared to control conditions (e.g., treatment as usual, supportive therapy) in targeting symptoms associated with personality disorders, including interpersonal difficulties, affective instability, identity disturbance, and impulsivity. Additionally, it examines potential moderators of treatment outcomes, such as treatment length, therapist experience, treatment fidelity, and participant characteristics (e.g., specific personality disorder diagnosis, comorbidities), to better understand the factors influencing the effectiveness of psychodynamic therapy for personality disorders.

Interpersonal Psychotherapy (IPT) has been recognized as an effective intervention for Major Depressive Disorder (MDD), focusing on interpersonal relationships and life events as triggers for depressive episodes. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of IPT in reducing depressive symptoms and improving social functioning in individuals with MDD. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of IPT compared to control conditions (e.g., waitlist, medication, other psychotherapies) in targeting symptoms of depression, including sadness, hopelessness, guilt, and interpersonal difficulties. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist experience, treatment fidelity, and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of IPT for MDD.

 Mindfulness-Based Stress Reduction (MBSR) has gained attention as an intervention for anxiety disorders, focusing on cultivating mindfulness skills to reduce symptoms of anxiety and enhance overall well-being. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of MBSR in reducing anxiety symptoms and improving quality of life in individuals with anxiety disorders. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of MBSR compared to control conditions (e.g., waitlist, treatment as usual) in targeting symptoms of anxiety, including generalized anxiety, panic attacks, and social anxiety. Additionally, it examines potential moderators of treatment outcomes, such as intervention length, frequency of mindfulness practice, therapist guidance, and participant characteristics (e.g., age, gender), to better understand the factors influencing the effectiveness of MBSR for anxiety disorders.

Acceptance and Commitment Therapy (ACT) has gained recognition as a promising intervention for treating depression, focusing on promoting psychological flexibility and values-based living. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ACT in reducing depressive symptoms and improving overall functioning in individuals with depression. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ACT compared to control conditions (e.g., treatment as usual, other psychotherapies) in targeting symptoms of depression, including sadness, anhedonia, guilt, and cognitive distortions. Additionally, it examines potential moderators of treatment outcomes, such as treatment format (individual vs. group), treatment duration, therapist adherence, and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of ACT for depression.

Dialectical Behavior Therapy (DBT) has gained recognition as a leading intervention for Borderline Personality Disorder (BPD), integrating cognitive-behavioral techniques with mindfulness and acceptance strategies. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of DBT in reducing BPD symptoms and improving overall functioning in individuals with BPD. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of DBT compared to control conditions (e.g., treatment as usual, other psychotherapies) in targeting symptoms of emotional dysregulation, impulsivity, self-harm, and interpersonal difficulties. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, adherence to the DBT model, therapist characteristics, and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of DBT for BPD.

Eye Movement Desensitization and Reprocessing (EMDR) has emerged as a prominent intervention for treating Post-Traumatic Stress Disorder (PTSD), employing bilateral stimulation to process traumatic memories and alleviate associated symptoms. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of EMDR in reducing PTSD symptoms and improving overall well-being in individuals with PTSD. Through an extensive literature review, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of EMDR compared to control conditions (e.g., waitlist, supportive therapy) in targeting PTSD symptoms, including re-experiencing, avoidance, negative alterations in cognition and mood, and hyperarousal. Additionally, it examines potential moderators of treatment outcomes, such as session length, therapist experience, treatment fidelity, and participant characteristics (e.g., trauma type, comorbidities), to enhance understanding of the factors influencing the effectiveness of EMDR for PTSD.

Cognitive Behavioral Therapy (CBT) has been established as a frontline intervention for Generalized Anxiety Disorder (GAD), targeting maladaptive thoughts and behaviors associated with excessive worry and anxiety. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of CBT in reducing anxiety symptoms and improving overall functioning in individuals with GAD. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of CBT compared to control conditions (e.g., waitlist, medication, other psychotherapies) in targeting symptoms of anxiety, worry, and associated impairments. Additionally, it examines potential moderators of treatment outcomes, such as treatment format (individual vs. group), therapist involvement, treatment duration, and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of CBT for GAD.

Applied Behavior Analysis (ABA) has been widely recognized as an effective intervention for addressing core symptoms of Autism Spectrum Disorder (ASD) in children, focusing on behavior modification and skill development. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ABA in improving communication, social interaction, and adaptive behavior in children with ASD. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ABA compared to control conditions (e.g., treatment as usual, developmental interventions) in targeting ASD symptoms and associated impairments. Additionally, it examines potential moderators of treatment outcomes, such as treatment intensity, duration, therapist training, and participant characteristics (e.g., age, cognitive level), to better understand the factors influencing the effectiveness of ABA for ASD.

Parent-Child Interaction Therapy (PCIT) has emerged as a leading intervention for addressing disruptive behavior disorders in children, focusing on improving parent-child interactions and reducing negative behaviors. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of PCIT in reducing disruptive behavior symptoms and improving parent-child relationships. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of PCIT compared to control conditions (e.g., waitlist, treatment as usual) in targeting disruptive behaviors, including aggression, defiance, and conduct problems. Additionally, it examines potential moderators of treatment outcomes, such as treatment format (individual vs. group), therapist involvement, parent training intensity, and participant characteristics (e.g., age, comorbidities), to better understand the factors influencing the effectiveness of PCIT for disruptive behavior disorders in children.

Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) has emerged as a leading intervention for addressing Post-Traumatic Stress Disorder (PTSD) symptoms in children and adolescents, integrating cognitive-behavioral techniques with trauma-specific components. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of TF-CBT in reducing PTSD symptoms and improving overall functioning in youth populations. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of TF-CBT compared to control conditions (e.g., waitlist, supportive therapy) in targeting PTSD symptoms, including re-experiencing, avoidance, negative alterations in cognition and mood, and hyperarousal. Additionally, it examines potential moderators of treatment outcomes, such as trauma type, treatment duration, parental involvement, and participant characteristics (e.g., age, gender, comorbidities), to better understand the factors influencing the effectiveness of TF-CBT for PTSD in children and adolescents.

Interpersonal Psychotherapy (IPT) has been recognized as an effective intervention for Major Depressive Disorder (MDD), focusing on interpersonal issues and relationships. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of IPT in reducing depressive symptoms and improving overall functioning in individuals with MDD. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of IPT compared to control conditions (e.g., treatment as usual, other psychotherapies) in targeting symptoms of depression, interpersonal functioning, and quality of life. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, therapist adherence, focus of interpersonal problems, and participant characteristics (e.g., age, gender), to better understand the factors influencing the effectiveness of IPT for MDD.

Mindfulness-Based Cognitive Therapy (MBCT) has garnered attention as a promising intervention for preventing relapse in depression, combining cognitive therapy techniques with mindfulness practices. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of MBCT in reducing relapse rates and improving overall well-being in individuals with a history of depression. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of MBCT compared to control conditions (e.g., treatment as usual, maintenance antidepressant medication) in targeting relapse/recurrence of depressive episodes, symptoms of depression, and quality of life. Additionally, it examines potential moderators of treatment outcomes, such as participant adherence, length of follow-up, frequency of mindfulness practice, and participant characteristics (e.g., age, number of prior depressive episodes), to better understand the factors influencing the effectiveness of MBCT for relapse prevention in depression.

Acceptance and Commitment Therapy (ACT) has emerged as a promising intervention for chronic pain management, focusing on psychological flexibility and values-based action. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ACT in reducing pain intensity and improving overall functioning in individuals with chronic pain. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ACT compared to control conditions (e.g., treatment as usual, active interventions) in targeting pain-related outcomes, including pain severity, pain interference, physical functioning, and emotional distress. Additionally, it examines potential moderators of treatment outcomes, such as intervention format (individual vs. group), treatment duration, therapist involvement, and participant characteristics (e.g., pain duration, comorbidities), to better understand the factors influencing the effectiveness of ACT for chronic pain management.