The Efficacy of Acceptance and Commitment Therapy (ACT) for Major Depressive Disorder (MDD) in Adults: A Meta-Analysis of Randomized Controlled Trials
Abstract
Acceptance and Commitment Therapy (ACT) has emerged as a promising intervention for Major Depressive Disorder (MDD) in adults, focusing on fostering psychological flexibility and promoting valued living. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of ACT in reducing depressive symptoms and improving overall functioning in adults with MDD. Through a thorough review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of ACT compared to control conditions (e.g., waitlist, treatment as usual) in targeting core symptoms of depression, including low mood, anhedonia, cognitive distortions, and functional impairment. Additionally, it examines potential moderators of treatment outcomes, such as intervention duration, session frequency, therapist competence, and participant characteristics (e.g., comorbidities, treatment history), to better understand the factors influencing the effectiveness of ACT for MDD in adults.
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References
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