The Effectiveness of Cognitive Remediation Therapy (CRT) for Schizophrenia: A Meta-Analysis of Randomized Controlled Trials
Abstract
Cognitive Remediation Therapy (CRT) has emerged as a promising intervention for addressing cognitive deficits in individuals with schizophrenia, aiming to improve cognitive functioning and functional outcomes. This meta-analysis of randomized controlled trials (RCTs) evaluates the efficacy of CRT in enhancing cognitive abilities and functional outcomes in individuals with schizophrenia. Through a comprehensive review of the literature, the meta-analysis synthesizes effect sizes from RCTs assessing the effectiveness of CRT compared to control conditions (e.g., treatment as usual, active control interventions) in targeting cognitive domains such as attention, memory, executive function, and social cognition. Additionally, it examines potential moderators of treatment outcomes, such as treatment duration, session frequency, therapist involvement, and participant characteristics (e.g., duration of illness, symptom severity), to better understand the factors influencing the effectiveness of CRT for schizophrenia.
Share and Cite
Article Metrics
References
- Wykes, T., et al. (2011). Cognitive remediation therapy for schizophrenia: Randomized controlled trial. British Journal of Psychiatry, 198(5), 398-403.
- McGurk, S. R., et al. (2007). Cognitive training for supported employment: 2-3 year outcomes of a randomized controlled trial. American Journal of Psychiatry, 164(3), 437-441.
- Kurtz, M. M., et al. (2009). Neurocognitive and social cognitive predictors of interpersonal skill in schizophrenia. Psychiatry Research, 167(1-2), 35-40.
- Twamley, E. W., et al. (2003). A review of cognitive training in schizophrenia. Schizophrenia Bulletin, 29(2), 359-382.
- Bowie, C. R., et al. (2012). Cognitive remediation for schizophrenia: An expert working group white paper on core techniques. Schizophrenia Research, 135(1-3), 18-27.
- Medalia, A., et al. (2017). Cognitive remediation in schizophrenia: Current status and future perspectives. Schizophrenia Research, 179, 1-3.