Antibiotic Resistance: Combatting a Global Health Threat
Abstract
Antibiotic resistance poses a significant global health threat, undermining the effectiveness of antibiotic treatments and leading to increased morbidity, mortality, and healthcare costs. This paper examines the multifaceted nature of antibiotic resistance, exploring its causes, mechanisms, and consequences for public health. Key topics include the misuse and overuse of antibiotics in human and animal healthcare, the spread of resistant pathogens through international travel and trade, and the emergence of multidrug-resistant bacterial strains. Additionally, the paper discusses strategies for combating antibiotic resistance, including antimicrobial stewardship programs, infection prevention and control measures, and the development of new antibiotics and alternative treatment approaches. Furthermore, the paper addresses the role of policy interventions, surveillance systems, and global collaboration in mitigating the spread of antibiotic-resistant infections and preserving the efficacy of existing antimicrobial agents. By synthesizing evidence from epidemiological studies, clinical trials, and policy analyses, this paper aims to raise awareness of antibiotic resistance as a critical public health issue and advocate for coordinated efforts to address this growing challenge.
Share and Cite
Article Metrics
References
- O'Neill, J. (2016). Tackling drug-resistant infections globally: final report and recommendations. Review on Antimicrobial Resistance.
- Ventola, C. L. (2015). The antibiotic resistance crisis: part 1: causes and threats. Pharmacy and Therapeutics, 40(4), 277-283.
- Laxminarayan, R., et al. (2013). Antibiotic resistance—the need for global solutions. The Lancet Infectious Diseases, 13(12), 1057-1098.
- World Health Organization. (2014). Antimicrobial resistance: global report on surveillance.
- Spellberg, B., et al. (2016). The future of antibiotics and resistance: a tribute to a career of leadership by John Bartlett. Clinical Infectious Diseases, 62(12), 1555-1560.
- Tacconelli, E., et al. (2018). Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis. The Lancet Infectious Diseases, 18(3), 318-327.
- Harbarth, S., et al. (2015). Antibiotic resistance: the complex interplay between infection, antibiotic treatment, and human behavior. Environmental Microbiology, 17(12), 1313-1323.
- Prestinaci, F., et al. (2015). Antimicrobial resistance: a global multifaceted phenomenon. Pathogens and Global Health, 109(7), 309-318.